Complete Clearance™ at BioReliance

We offer a “Complete Clearance” service, where our highly experienced process scientists will perform all process steps on behalf of the client. These include inactivation, filtration and chromatography studies. The services can be tailored to suit the needs of the client’s project with flexibility and a great choice of service. All services are fully validated and GLP compliant with dedicated QA personnel.

Our dedicated team has extensive experience in viral activation and removal process:

• Nanofiltration
• Column chromatography
• Pasteurisation
• Ethanol fractionation
• Viral in activation by treatment with solvent/detergent and extreme pH
• Photoactivation
• UV treatment
• Cleaning studies
• Column re-use studies

Multiple steps are taken to ensure comparability:

• Technical discussions
• Review of client’s SOPs
• Preparation of customised workbooks
• Technical transfer studies
• Mock runs