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+44 (0)141 946 9999

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Binding Assays

The extensive variability of a molecule's physicochemical and structural design creates extensive diversity in the activity of Fc receptors, altering the antibody effector function. The Fc receptors play a critical role in the function of therapeutic antibodies as they can bind to a variety of receptors and other protein components within the immune system. We have prepared a wide variety of assays to determine the kinetics of various receptors. Our Fc gamma receptors and FcRn assays have been developed with surface plasmon resonance, on Biacore®, for quick results while maintaining robust information. We can also tailor specific affinity testing to target antigens as needed.

Our tests include:

  • Affinity with Surface Plasmon Resonance
  • Fcɣ RI
  • Fcɣ RIIA
  • Fcɣ RIIB
  • Fcɣ RIIIA
  • Fcɣ RIIIB
  • FcRn
  • Target Antigen
  • C1Q Binding ELISA

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