iNet Login|
United Kingdom
Pharma & Biopharma Manufacturing & Testing Services
Contact Us +44 (0)141 946 9999


Contact Us


+44 (0)141 946 9999

Tel +44 (0)141 946 9999


Request Information

General Inquiries

Physicochemical and Structural Assays

Physicochemical and structural assays often demand a broad variety of techniques and instrumentation for a complete analysis of drug purity, identity, and stability. We have years of experience with low complexity through high complexity assays for both R&D and GMP purposes to support data requirements at all steps of the development cycle. These assays can also be incorporated into a product’s lot release testing program. Experienced scientists will work with you to design a product characterization testing program customized to fit your needs and meet regulatory standards as provided in ICH Q6B guidelines. With state-of-the-art instrumentation and fast turnaround times, we are well-equipped to provide you reliable results to push your project forward.

Our tests include:

  • Higher Order Structure
  • Purity
  • Aggregates
  • Amino Acid Sequence
  • Amino Acid Composition
  • Terminal Amino Acid Sequence
  • Peptide Map
  • Sulfhydryl Group (Free Thiol Analysis)
  • Disulfide Bridges
  • Carbohydrate Structure
    • Monosaccharide Analysis
    • Glycan Profile
    • Glycan Linkage Analysis
  • Sialic Acid Quantification
  • Molecular Weight and Size
  • Isoform Pattern Analysis (Charge Profile)
  • Extinction Coefficient
  • Electrophoretic Patterns
  • Liquid Chromatographic Patterns

Our choice of multiple platforms gives you specific and sensitive outputs:

Click here for additional analytic capabilities.

Copyright © 2017 Sigma-Aldrich Co. LLC.  All Rights Reserved. Reproduction of any materials from the site is strictly forbidden without permission.  Sigma-Aldrich brand products are sold exclusively through Sigma-Aldrich Co. LLC. Sigma-Aldrich Corp. is a subsidiary of Merck KGaA, Darmstadt, Germany  Terms | Privacy