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Contact Us

Phone

+44 (0)141 946 9999

Tel +44 (0)141 946 9999

Email

info@bioreliance.com

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Physicochemical and Structural Assays

Physicochemical and structural assays often demand a broad variety of techniques and instrumentation for a complete analysis of drug purity, identity, and stability. We have years of experience with low complexity through high complexity assays for both R&D and GMP purposes to support data requirements at all steps of the development cycle. These assays can also be incorporated into a product’s lot release testing program. Experienced scientists will work with you to design a product characterization testing program customized to fit your needs and meet regulatory standards as provided in ICH Q6B guidelines. With state-of-the-art instrumentation and fast turnaround times, we are well-equipped to provide you reliable results to push your project forward.

Our tests include:

  • Higher Order Structure
  • Purity
  • Aggregates
  • Amino Acid Sequence
  • Amino Acid Composition
  • Terminal Amino Acid Sequence
  • Peptide Map
  • Sulfhydryl Group (Free Thiol Analysis)
  • Disulfide Bridges
  • Carbohydrate Structure
    • Monosaccharide Analysis
    • Glycan Profile
    • Glycan Linkage Analysis
  • Sialic Acid Quantification
  • Molecular Weight and Size
  • Isoform Pattern Analysis (Charge Profile)
  • Extinction Coefficient
  • Electrophoretic Patterns
  • Liquid Chromatographic Patterns

Our choice of multiple platforms gives you specific and sensitive outputs:
MS HDX, cIEF, SDS-PAGE, HPLC/UHPLC/UPLC, CE-SDS, SEC-MALS


Click here for additional analytic capabilities.

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